Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533860 | 0.82 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MAPTRXFP1CES1 | |
| SCHEMBL9538018 | 0.81 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9560768 | 0.76 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1CES1FAAH | |
| SCHEMBL9536204 | 0.75 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9533721 | 0.72 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL9531617 | 0.72 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL9534476 | 0.70 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560084 | 0.67 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL9532623 | 0.67 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL125952 | 0.67 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |