Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925768 | 0.82 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1 | |
| SCHEMBL9430241 | 0.81 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1 | |
| SCHEMBL9503905 | 0.81 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1 | |
| SCHEMBL9357210 | 0.80 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561489 | 0.80 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561427 | 0.80 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561413 | 0.80 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560059 | 0.78 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL9356898 | 0.78 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9428284 | 0.77 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189226-A | Chemical intermediate for diacid | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0365149-A2 | Leukotriene antagonist prodrugs | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |