Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535196 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BMAPTRAB9ANPC1 | |
| SCHEMBL3424244 | 0.77 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3426361 | 0.74 | TDP1 (0.47) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4291161 | 0.74 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10457876 | 0.74 | TDP1 (0.47) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10459037 | 0.73 | CYP1A1 (0.45) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3423108 | 0.73 | TDP1 (0.45) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10459036 | 0.73 | CYP1A1 (0.45) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3501694 | 0.70 | TSHR (0.50) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9877670 | 0.70 | TOP2A (0.51) | MAPTRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5023253-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |