Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530533 | 0.95 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9534113 | 0.90 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL9534123 | 0.89 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9531346 | 0.89 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL9532373 | 0.87 | SLC33A1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9534439 | 0.87 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL9531528 | 0.86 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9530720 | 0.85 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL9533549 | 0.85 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9533751 | 0.82 | AGTR1 (0.37) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | claimed |
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |