Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537442 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL9537667 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1PTGES2ALDH1A1PLA2G7 | |
| SCHEMBL9540058 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL9536230 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1PLA2G7 | |
| SCHEMBL9537417 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1PLA2G7 | |
| SCHEMBL9535031 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1PTGES2 | |
| SCHEMBL9536821 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL9537176 | 0.79 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL9536928 | 0.79 | PTGS2 (0.54) | PTGS2PTGS1PLA2G7 | |
| SCHEMBL9538909 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |