Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | MPC2 | O95563 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699229 | 0.87 | PPARG (0.63) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL8523496 | 0.85 | PPARG (0.58) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL1072226 | 0.82 | FFAR1 (0.77) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL9535414 | 0.82 | PPARG (0.38) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL8458411 | 0.82 | PPARG (0.74) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL12521898 | 0.80 | PPARG (0.62) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL9121895 | 0.79 | PPARG (0.66) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL1847053 | 0.77 | PPARG (0.67) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL9536496 | 0.77 | PPARG (0.61) | PPARGFFAR1RARGRXRAPPARA | |
| SCHEMBL6977977 | 0.77 | PPARG (0.66) | PPARGFFAR1RARGRXRAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |