Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 2/20 | 0.43 |
| ▸ | USP10 | Q14694 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535068 | 0.90 | MAPT (0.52) | MAPTPOLBL3MBTL1USP7USP10 | |
| SCHEMBL9534376 | 0.87 | MAPK14 (0.46) | MAPTALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL9535727 | 0.85 | ALDH1A1 (0.40) | MAPTUSP7USP10USP47ALDH1A1 | |
| SCHEMBL9538792 | 0.85 | MAPT (0.40) | MAPTUSP7USP10USP47ALDH1A1 | |
| SCHEMBL9537015 | 0.85 | MAPK14 (0.48) | MAPTALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL9538516 | 0.82 | MAPT (0.45) | MAPTPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9536752 | 0.82 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL9535539 | 0.82 | MAPK14 (0.42) | MAPTALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL9536872 | 0.80 | USP7 (0.41) | MAPTUSP7USP10USP47ALDH1A1 | |
| Diethylamine SCHEMBL9537391 | 0.79 | MAPK14 (0.41) | MAPTALDH1A1KDM4EHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |