Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | CES1 | P23141 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12757602 | 0.90 | CES1 (0.81) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28121846 | 0.90 | HTT (0.71) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29246542 | 0.90 | HTT (0.71) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL97106 | 0.90 | NPSR1 (0.56) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2831972 | 0.90 | CA12 (0.68) | CYP2C9HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL3919353 | 0.90 | CA1 (0.69) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6831830 | 0.90 | CA12 (0.68) | CYP2C9HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL18395077 | 0.90 | CES1 (0.81) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31198182 | 0.90 | HSD17B2 (0.66) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25212958 | 0.90 | PKM (0.74) | SMN1; SMN2IDO1PKMMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107372504-B | Application of sulfonamide compound in enhancing plant stress resistance and medicament containing same | 华中师范大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-107382842-B | Sulfonamide compound, use thereof, and pharmaceutical agent containing the same | 华中师范大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-107372504-A | Application of the sulfamide compound in stress resistance of plant is strengthened and the medicament containing the compound | 华中师范大学 | 2017-11-24 | — | — | CN | disclosed |
| EP-0352083-B1 | Alkenyltetrazole derivatives, their preparation and use | SHIONOGI & CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-4916231-A | THROMBOXANE A2 RECPTOR ANTAGONISTS | SHIONOGI & CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0352083-A2 | Alkenyltetrazole derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |