Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985049 | 0.95 | KCNH2 (0.65) | KCNH2NR4A2MAPK1SSTR5 | |
| Fumaric Acid SCHEMBL10384102 | 0.92 | KCNH2 (0.52) | KCNH2NR4A2MAPK1CHEK2SSTR5 | |
| SCHEMBL9536919 | 0.84 | KCNH2 (0.58) | KCNH2NR4A2SSTR5MEN1KMT2A | |
| Oxalic Acid SCHEMBL10384126 | 0.81 | KCNH2 (0.50) | KCNH2NR4A2HPGDMEN1KMT2A | |
| Oxalic Acid SCHEMBL10384125 | 0.81 | KCNH2 (0.50) | KCNH2NR4A2HPGDMEN1KMT2A | |
| SCHEMBL14173522 | 0.81 | KCNH2 (0.61) | KCNH2NR4A2CHEK2SSTR5ALDH1A1 | |
| SCHEMBL9534952 | 0.81 | KCNH2 (0.61) | KCNH2NR4A2SSTR5HPGDCYP3A4 | |
| SCHEMBL7981124 | 0.81 | KCNH2 (0.61) | KCNH2NR4A2SSTR5CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9631298 | 0.80 | KCNH2 (0.90) | KCNH2NR4A2SSTR5MEN1CYP3A4 | |
| SCHEMBL13319057 | 0.80 | KCNH2 (0.63) | KCNH2NR4A2SSTR5HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |