Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116010 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2CYP1A2GAA | |
| Iodide SCHEMBL11657801 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2CYP1A2GAA | |
| Iodide SCHEMBL11657794 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2CYP1A2GAA | |
| SCHEMBL11061798 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2CYP1A2GAA | |
| SCHEMBL15413417 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP1A2GAACYP2D6 | |
| SCHEMBL15413419 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP1A2GAACYP2D6 | |
| SCHEMBL906226 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRSMN1; SMN2GAAMAPT | |
| SCHEMBL7759973 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2GAAMAPT | |
| SCHEMBL11498267 | 0.72 | TSHR (0.39) | ALDH1A1TSHRSMN1; SMN2MAPTFAAH | |
| SCHEMBL11673949 | 0.71 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182262-B1 | NONA AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| EP-0182262-A2 | Nona and decapeptide analogs of LHRH useful as LHRH antagonists | SYNTEX (U.S.A.) INC. (US) | 1986-05-28 | — | — | EP | disclosed |