Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443780 | 0.86 | AOC3 (0.63) | KDM4EGAASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL5076851 | 0.81 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1AOC3L3MBTL1 | |
| SCHEMBL5073667 | 0.81 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1AOC3L3MBTL1 | |
| SCHEMBL2673557 | 0.81 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1AOC3L3MBTL1 | |
| SCHEMBL4723219 | 0.79 | CNR2 (0.49) | KDM4EGAASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL3443103 | 0.78 | AOC3 (0.67) | KDM4ETDP1AOC3L3MBTL1ADRB3 | |
| SCHEMBL937188 | 0.76 | KMT2A (0.49) | KDM4ESMN1; SMN2ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL936475 | 0.76 | KMT2A (0.49) | KDM4ESMN1; SMN2ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL936476 | 0.76 | KMT2A (0.49) | KDM4ESMN1; SMN2ALDH1A1KMT2ACYP2C9 | |
| Anisaldehyde SCHEMBL20357563 | 0.74 | ALDH1A1 (0.83) | TDP1ALDH1A1CYP2A6KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |