SCHEMBL9536202

SCHEMBL9536202

CSc1nc(=O)[nH]nc1N

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NUDT1 P36639 1/20 0.31
GAA P10253 1/20 0.30
MAP3K5 Q99683 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692506 0.72
SCHEMBL9535333 0.67
SCHEMBL8912039 0.67
SCHEMBL21280025 0.59 KDM4E (0.35)
SCHEMBL30818434 0.58
SCHEMBL31387681 0.58 HSP90AB1 (0.37) MEN1KMT2AMAP3K5
SCHEMBL10753654 0.58 HSP90AB1 (0.37) MEN1KMT2AMAP3K5
SCHEMBL9210531 0.58
SCHEMBL10481862 0.57 MAPT (0.33) GAA
SCHEMBL11171773 0.57 MAPT (0.40) MEN1KMT2ANUDT1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0177016-B1 PYRIDYLOXY DERIVATIVES Ikeda Mohando Co., Ltd. (JP) 1993-06-23 EP disclosed
US-4710498-A ANTIULCER AGENTS IKEDA MOHANDO CO., LTD. (JP) 1987-12-01 US disclosed
EP-0177016-A2 Pyridyloxy derivatives Ikeda Mohando Co., Ltd. (JP) 1986-04-09 EP disclosed