⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912039 | 0.77 | — | — | |
| SCHEMBL9535333 | 0.77 | — | — | |
| SCHEMBL9536202 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL30818434 | 0.72 | — | — | |
| SCHEMBL7587289 | 0.59 | CHEK1 (0.39) | — | |
| SCHEMBL10414868 | 0.58 | NQO1 (0.50) | — | |
| SCHEMBL5143009 | 0.58 | — | — | |
| SCHEMBL8505096 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL8723152 | 0.58 | CHEK1 (0.38) | — | |
| SCHEMBL20383314 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |