Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781958 | 0.81 | MAPT (0.48) | GAAMAPT | |
| SCHEMBL8334125 | 0.81 | MAPT (0.48) | GAAMAPT | |
| SCHEMBL9935465 | 0.81 | MAPT (0.48) | GAAMAPT | |
| SCHEMBL11298721 | 0.77 | GAA (0.44) | GAAMAPT | |
| SCHEMBL27287397 | 0.77 | MAPT (0.44) | GAAMAPT | |
| SCHEMBL4714931 | 0.76 | MAPT (0.42) | GAAMAPT | |
| SCHEMBL4770305 | 0.76 | GAA (0.47) | GAAMAPT | |
| SCHEMBL1246857 | 0.75 | GAA (0.46) | GAAMAPT | |
| SCHEMBL27316259 | 0.75 | MAPT (0.41) | GAAMAPT | |
| SCHEMBL29605097 | 0.75 | MAPT (0.54) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384677-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0384676-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-11-10 | — | — | EP | disclosed |
| US-4981848-A | CARDIOVASCULAR, HYPOTENSIVE, ANTIDEPRESSANT | SMITHKLINE BEECHAM CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4981849-A | OBESITY, DIABETES, CARDIOVASCULAR DISORDERS, DEPRESSION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0384677-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0384676-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |