Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316348 | 0.81 | MAPT (0.43) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL8334125 | 0.77 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL8781958 | 0.77 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9935465 | 0.77 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9536334 | 0.77 | GAA (0.48) | MAPTGAA | |
| SCHEMBL1247317 | 0.74 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL11298721 | 0.73 | GAA (0.44) | MAPTGAA | |
| SCHEMBL4714931 | 0.72 | MAPT (0.42) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL4770305 | 0.72 | GAA (0.47) | MAPTGAA | |
| SCHEMBL1246857 | 0.71 | GAA (0.46) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038099-A | Alpha-adrenergic aceptor antagonist | SMITHKLINE BECKMAN CORP (US) | 1989-12-20 | — | — | CN | disclosed |