Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9432208 | 0.99 | GAA (0.44) | GAAPTK2ALKSLC2A1PDE4B | |
| SCHEMBL9431368 | 0.87 | SLC2A1 (0.52) | PTK2SLC2A1PDE4BPDE7ACSNK2A1 | |
| SCHEMBL9536391 | 0.84 | SLC2A1 (0.46) | SLC2A1PDE4BPDE7ACSNK2A1CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9431893 | 0.83 | SLC2A1 (0.48) | SLC2A1PDE4BPDE7ACSNK2A1CSNK2A2 | |
| Hydrochloric Acid SCHEMBL10441160 | 0.83 | SLC2A1 (0.48) | SLC2A1PDE4BPDE7ACSNK2A1CSNK2A2 | |
| SCHEMBL9431929 | 0.83 | GAA (0.46) | GAAPRKDC | |
| SCHEMBL9432574 | 0.82 | GAA (0.43) | GAACSNK2A1PRKDC | |
| Hydrochloric Acid SCHEMBL9776765 | 0.81 | SLC2A1 (0.66) | SLC2A1 | |
| SCHEMBL9536374 | 0.79 | TUBB4A (0.52) | — | |
| Hydrochloric Acid SCHEMBL9432210 | 0.79 | TUBB4A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404356-B1 | SUBSTITUTED THIENOPYRIMIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USE | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-22 | — | — | EP | claimed |