SCHEMBL95366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3939329	0.88	PGK1 (0.46)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL95365	0.86	TSHR (0.41)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL5246523	0.82	MAPT (0.41)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL95088	0.81	NOTUM (0.49)	NOTUMTSHRLMNAMAPTTP53
	SCHEMBL95451	0.74	MAPT (0.38)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL95450	0.72	MAPT (0.41)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL24922864	0.71	NOTUM (0.63)	NOTUMTSHRRAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2097697	0.70	TSHR (0.40)	TSHRLMNAMAPTTP53KDM4E
	SCHEMBL6527881	0.70	NOTUM (0.70)	NOTUMTSHRLMNAMAPTHPGD
	SCHEMBL95230	0.70	NOTUM (0.44)	NOTUMTSHRLMNAMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.