Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXO1 | Q12778 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537372 | 0.89 | CACNA1F (0.47) | FOXO1CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9536591 | 0.87 | CACNA1F (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9535876 | 0.80 | KDM4E (0.48) | POLBKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL10683743 | 0.76 | POLB (0.52) | FOXO1CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10680723 | 0.76 | KDM4E (0.54) | FOXO1CACNA1FPOLBMAPK1CACNA1D | |
| Hydrochloric Acid SCHEMBL9688844 | 0.75 | POLB (0.52) | FOXO1CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9536474 | 0.75 | CACNA1F (0.64) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9535484 | 0.75 | DRD3 (0.59) | MAPK1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6720755 | 0.75 | KDM4E (0.53) | FOXO1CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9689732 | 0.75 | KCNH2 (0.51) | FOXO1CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |