Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 16/20 | 0.55 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536591 | 0.88 | CACNA1F (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9537372 | 0.86 | CACNA1F (0.47) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9692605 | 0.85 | CACNA1F (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9541515 | 0.83 | MEN1 (0.46) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9241429 | 0.83 | ALDH1A1 (0.54) | POLBKCNH2TOP2ATOP2BMEN1 | |
| SCHEMBL9757458 | 0.82 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9426331 | 0.81 | CACNA1F (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL5868656 | 0.81 | POLB (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9788920 | 0.81 | CACNA1F (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10686828 | 0.81 | CACNA1F (0.74) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |