Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723110 | 0.72 | PARP1 (0.47) | PARP1 | |
| SCHEMBL13259202 | 0.69 | KDM4E (0.41) | — | |
| SCHEMBL20523017 | 0.69 | — | — | |
| SCHEMBL917625 | 0.68 | PARP1 (0.43) | PARP1 | |
| SCHEMBL29973298 | 0.68 | PARP1 (0.33) | PARP1MCL1DAOAURKAAURKB | |
| SCHEMBL24112888 | 0.68 | ADRA1A (0.34) | PARP1JAK2AURKAAURKBINCENP | |
| SCHEMBL30559735 | 0.68 | TNF (0.36) | — | |
| SCHEMBL2732443 | 0.67 | PARP1 (0.32) | PARP1MCL1DAOAURKAAURKB | |
| SCHEMBL25365116 | 0.67 | PARP1 (0.42) | PARP1 | |
| SCHEMBL31208007 | 0.67 | PARP1 (0.42) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119351-A1 | GPR139 AGONIST | 深圳湾实验室 | 2025-06-12 | — | — | WO | disclosed |
| WO-2025064535-A1 | TRICYCLIC SUBSTITUTED AMINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | WO | disclosed |
| EP-0558521-A1 | ISONICOTINIC ACID DERIVATIVES AND RELATED SPIRO COMPOUNDS WITH HERBICIDAL ACTION | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-09-08 | — | — | EP | disclosed |