Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382659 | 0.90 | MAOB (0.64) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL9533962 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL9534068 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL9532937 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL9534595 | 0.87 | MAOB (0.59) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL10381175 | 0.87 | MAOB (0.59) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL10381297 | 0.84 | MAOB (0.57) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL10381326 | 0.84 | MAOB (0.60) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL9532759 | 0.84 | MAOB (0.59) | MAOBMEN1KMT2AGAAMAPT | |
| SCHEMBL5775147 | 0.84 | MAOB (0.59) | MAOBMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| WO-1990001481-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1990-02-22 | — | — | WO | disclosed |