Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060028 | 0.91 | MAPT (0.45) | CHRM3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL9059545 | 0.84 | MAPT (0.45) | CHRM3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL9059993 | 0.84 | CHRM3 (0.57) | CHRM3ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL9059781 | 0.81 | CHRM3 (0.53) | CHRM3ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL9059684 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHSD17B10GAA | |
| SCHEMBL9059638 | 0.78 | MEN1 (0.38) | CHRM3ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9536114 | 0.76 | CHRM3 (0.47) | CHRM3ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL9059166 | 0.76 | CHRM3 (0.52) | CHRM3ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL9059333 | 0.75 | CHRM3 (0.52) | CHRM3KDM4E | |
| SCHEMBL9059302 | 0.74 | MAPK1 (0.52) | CHRM3ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |