Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8736411 | 0.98 | AXL (0.41) | AXLPLK4FPR3FPR2CHEK2 | |
| SCHEMBL2247061 | 0.89 | PDK2 (0.47) | PLK4PDK2EPHX1HTR6 | |
| SCHEMBL21460246 | 0.84 | PDK2 (0.43) | AXLPLK4CHEK2CHEK1PRKCZ | |
| SCHEMBL21460364 | 0.82 | PDK2 (0.42) | AXLPLK4CHEK2CHEK1PRKCZ | |
| SCHEMBL6216444 | 0.81 | POLB (0.50) | AXLPLK4CHEK2HTR6 | |
| SCHEMBL4131760 | 0.81 | ITK (0.50) | AXLPLK4CHEK2ITKKCNH2 | |
| SCHEMBL2305510 | 0.81 | AXL (0.42) | AXLPLK4FPR3FPR2CHEK1 | |
| SCHEMBL5392079 | 0.81 | PLK4 (0.56) | AXLPLK4FPR3FPR2PRKCZ | |
| SCHEMBL28266386 | 0.81 | AXL (0.42) | AXLPLK4FPR3FPR2CHEK1 | |
| SCHEMBL4634218 | 0.81 | HTR6 (0.46) | AXLPLK4CHEK2CHEK1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |