Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 16/20 | 0.82 |
| ▸ | FPR1 | P21462 | 6/20 | 0.82 |
| ▸ | PPIA | P62937 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.79 |
| ▸ | GMNN | O75496 | 1/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | RARB | P10826 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.79 |
| ▸ | TACR2 | P21452 | 1/20 | 0.79 |
| ▸ | PPIB | P23284 | 1/20 | 0.79 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953685 | 1.00 | ABCB1 (0.82) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL13379663 | 1.00 | ABCB1 (0.82) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL13379674 | 0.96 | ABCB1 (0.76) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL13379673 | 0.96 | ABCB1 (0.76) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL13379677 | 0.95 | PPIA (0.81) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL13379672 | 0.94 | ABCB1 (0.82) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL439348 | 0.93 | ABCB1 (0.89) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL22032784 | 0.93 | ABCB1 (0.89) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL954591 | 0.93 | ABCB1 (0.72) | ABCB1FPR1PPIAMEN1NPC1 | |
| SCHEMBL954590 | 0.93 | ABCB1 (0.72) | ABCB1FPR1PPIAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957518-B1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8252895-B2 | Cyclic peptide compounds | ASTELLAS PHARMA INC. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-7872097-B2 | Cyclic peptide compounds | ASTELLAS PHARMA INC. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20100286033-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC. | 2010-11-11 | — | — | US | disclosed |
| US-7696167-B2 | Cyclic peptide compound | ASTELLAS PHARMA INC. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7696167-B2 | Cyclic peptide compound | ASTELLAS PHARMA INC. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20090170755-A1 | Cyclic Peptide Compounds | ASTELLAS PHARMA INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20080214447-A1 | Cyclic Peptide Compound | ASTELLAS PHARMA INC. (JP) | 2008-09-04 | — | — | US | disclosed |
| US-20080214447-A1 | Cyclic Peptide Compound | ASTELLAS PHARMA INC. (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170755-A1 | Cyclic Peptide Compounds | VIP, HAVCR2, EIF2AK2 | ABCB1 3186/4885FPR1 1063/4885PPIA 1681/4885 |
| US-20100286033-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | VIP, HAVCR2, EIF2AK2 | ABCB1 3433/4885FPR1 1256/4885PPIA 1850/4885 |
| US-20080214447-A1 | Cyclic Peptide Compound | VIP, NGLY1, PROKR1 | ABCB1 3198/4885FPR1 217/4885PPIA 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.