Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.89 |
| ▸ | PPIA | P62937 | 5/20 | 0.86 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.86 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.86 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.86 |
| ▸ | MEN1 | O00255 | 1/20 | 0.86 |
| ▸ | NPC1 | O15118 | 1/20 | 0.86 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.86 |
| ▸ | GMNN | O75496 | 1/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | MAPT | P10636 | 1/20 | 0.86 |
| ▸ | RARB | P10826 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.86 |
| ▸ | TACR2 | P21452 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032784 | 1.00 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL18163232 | 0.98 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL1708943 | 0.98 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL101371 | 0.98 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL16596082 | 0.96 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL19646863 | 0.96 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL22033395 | 0.96 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL102191 | 0.96 | ABCB1 (0.89) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL23109977 | 0.94 | ABCB1 (0.79) | ABCB1PPIAABCC1ABCC2FKBP1B | |
| SCHEMBL13379663 | 0.93 | ABCB1 (0.82) | ABCB1PPIAABCC1ABCC2FKBP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689758-B | Device and method for checking the effect of a drug on microorganisms | 上海宜晟生物科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-115266996-B | Analysis method and application of related substances in cyclosporine A preparation | 兆科（广州）眼科药物有限公司 | 2024-04-30 | — | — | CN | claimed |
| US-11725227-B2 | Devices and methods for examining drug effects on microorganisms | ESSENLIX CORPORATION (US) | 2023-08-15 | — | — | US | claimed |
| CN-115266996-A | Analysis method and application of related substances in cyclosporin A preparation | 兆科（广州）眼科药物有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115094108-A | Paecilomyces lilacinus and application thereof in production of cyclosporine C and prevention and control of bemisia tabaci | 华南农业大学 | 2022-09-23 | — | — | CN | claimed |
| US-20200399675-A1 | DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS | ESSENLIX CORPORATION (US) | 2020-12-24 | — | — | US | claimed |
| WO-2019028133-A1 | DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS | ESSENLIX CORPORATION (US) | 2019-02-07 | — | — | WO | claimed |
| EP-2931299-B1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LTD (GB) | 2019-02-06 | — | — | EP | claimed |
| WO-2015193673-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LIMITED (GB) | 2015-12-23 | — | — | WO | claimed |
| US-20150313959-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LTD (GB) | 2015-11-05 | — | — | US | claimed |
| EP-0375454-B1 | ENZYME-LINKED IMMUNOASSAY FOR MEASUREMENT OF CYCLOSPORIN A LEVELS IN WHOLE BLOOD SAMPLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1992016226-A1 | IL-1 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-10-01 | — | — | WO | claimed |
| US-5151348-A | Lysis red blood cells, contacting with galactosidase labeled anticyclosporin antibodies | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-29 | — | — | US | claimed |
| US-5047396-A | Cyclosporins, monester of hydroxylated fatty acid with ethylene glycol and mono or polyvalent alcohols | BIOGAL GYOGYSZERGYAR (HU) | 1991-09-10 | — | — | US | claimed |
| EP-0379708-A1 | Fungi strain Tolypocladiam varium and process for obtaining complexes of antibiotic cyclosporin and/or its components | BIOGAL GYOGYSZERGYAR (HU) | 1990-08-01 | — | — | EP | claimed |
| EP-0375454-A1 | Enzyme-linked immunoassay for measurement of cyclosporin A levels in whole blood samples | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1990000389-A1 | FREEZE-DRIED LIPOSOME COMPOSITIONS CONTAINING CYCLOSPORIN | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-01-25 | — | — | WO | claimed |
| US-4727035-A | RADIOACTIVE OR FLUORESCENT LABELS | SANDOZ LTD. (CH) | 1988-02-23 | — | — | US | claimed |
| US-4210581-A | CYCLOSPROINS USEFUL AS IMMUNOSUPPRESSIVES | SANDOZ LTD. (CH) | 1980-07-01 | — | — | US | claimed |
| US-4108985-A | IMMUNOSUPPRESIVE AGENTS | SANDOZ LTD. (CH) | 1978-08-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150313959-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PPIL1, PPIG, PPID | ABCB1 158/4885PPIA 12/4885ABCC1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.