Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 5/20 | 0.51 |
| ▸ | DHFR | P00374 | 3/20 | 0.48 |
| ▸ | FPGS | Q05932 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536834 | 0.94 | GART (0.57) | GARTDHFRATIC | |
| SCHEMBL9536050 | 0.93 | GART (0.50) | GARTDHFRFPGSATIC | |
| SCHEMBL9535149 | 0.91 | GART (0.52) | GARTDHFRFPGSATIC | |
| SCHEMBL9536040 | 0.88 | GART (0.56) | GARTDHFRATIC | |
| SCHEMBL9535135 | 0.85 | GART (0.58) | GARTDHFRATIC | |
| SCHEMBL9536782 | 0.84 | GART (0.68) | GARTDHFRFPGSATIC | |
| SCHEMBL9535744 | 0.83 | GART (0.51) | GARTDHFRFPGSATIC | |
| SCHEMBL9527114 | 0.83 | GART (0.62) | GARTDHFRFPGSATIC | |
| SCHEMBL10808300 | 0.83 | GART (0.62) | GARTDHFRATIC | |
| SCHEMBL10479205 | 0.80 | GART (0.57) | GARTATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215063-B1 | PYRIDO (2,3-d )PYRIMIDIN DERIVATIVES | UNIV PRINCETON (US) | 1993-11-03 | — | — | EP | claimed |