Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | EDNRA | P25101 | 1/20 | 0.67 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TOP2A | P11388 | 5/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508694 | 0.96 | LMNA (0.63) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL4902751 | 0.93 | LMNA (0.66) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9538141 | 0.93 | LMNA (0.66) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9539001 | 0.91 | KMT2A (0.55) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9536803 | 0.90 | KMT2A (0.55) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11017455 | 0.89 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11017256 | 0.89 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10508083 | 0.88 | KMT2A (0.53) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10510785 | 0.88 | KMT2A (0.53) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10904089 | 0.88 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101792443-A | Fluoro-carbostyril derivative as well as preparation method and application thereof | OKEANOS TECH CO LTD | 2010-08-04 | — | — | CN | disclosed |
| EP-0153580-B2 | NAPHTHYRIDINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0153580-B1 | NAPHTHYRIDINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4616019-A | ANTIBIOTIC | ABBOTT LABORATORIES (US) | 1986-10-07 | — | — | US | disclosed |
| EP-0153580-A1 | Naphthyridine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-04 | — | — | EP | disclosed |