Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536981 | 0.87 | PTGS2 (0.51) | ADRB3PTGS1PTGS2 | |
| SCHEMBL9537176 | 0.84 | PTGS2 (0.54) | ADRB3PTGS1PTGS2 | |
| SCHEMBL5674482 | 0.81 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL9538310 | 0.80 | PTGS2 (0.48) | PTGS1PTGS2NR3C1 | |
| SCHEMBL9536821 | 0.79 | PTGS2 (0.56) | PTGS1PTGS2 | |
| SCHEMBL9540058 | 0.78 | PTGS2 (0.55) | PTGS1PTGS2 | |
| SCHEMBL9536630 | 0.78 | MAPT (0.48) | PTGS1PTGS2 | |
| SCHEMBL9537417 | 0.76 | PTGS2 (0.55) | PTGS1PTGS2 | |
| SCHEMBL9536986 | 0.74 | PTGS1 (0.48) | PTGS1PTGS2 | |
| SCHEMBL9868559 | 0.74 | PTGS2 (0.48) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |