Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27274512 | 0.87 | SMN1; SMN2 (0.53) | PRKCIALDH1A1SMN1; SMN2HPGDNEU3 | |
| SCHEMBL1474880 | 0.81 | SMN1; SMN2 (0.54) | PRKCIALDH1A1SMN1; SMN2HPGDNEU3 | |
| SCHEMBL9624564 | 0.80 | SMN1; SMN2 (0.53) | PRKCIALDH1A1SMN1; SMN2HPGDNEU3 | |
| SCHEMBL5674438 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL9624571 | 0.80 | SMN1; SMN2 (0.53) | PRKCIALDH1A1SMN1; SMN2HPGDNEU3 | |
| SCHEMBL3249787 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDNEU3KDM4E | |
| SCHEMBL8887638 | 0.79 | PTGER4 (0.64) | ALDH1A1SMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL2245773 | 0.79 | PRKCI (1.00) | PRKCIALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL7110796 | 0.79 | ALDH1A1 (0.51) | PRKCIALDH1A1SMN1; SMN2HPGDNEU3 | |
| SCHEMBL9535456 | 0.79 | AKR1C3 (0.60) | ALDH1A1SMN1; SMN2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |