Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HLA-A | P04439 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9536567 | 0.95 | HRH1 (0.47) | SSTR5HRH1CYP2D6KCNH2CHRM1 | |
| Oxalic Acid SCHEMBL9536571 | 0.95 | HRH1 (0.47) | SSTR5HRH1CYP2D6KCNH2CHRM1 | |
| SCHEMBL9535231 | 0.86 | HRH3 (0.52) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9537288 | 0.85 | SSTR5 (0.53) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9536663 | 0.84 | RAB9A (0.55) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9537554 | 0.84 | HRH1 (0.63) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL9537670 | 0.84 | RAB9A (0.55) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9536807 | 0.84 | SSTR5 (0.50) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9537438 | 0.84 | HRH1 (0.55) | RAB9ASSTR5HRH1CYP2D6KCNH2 | |
| SCHEMBL9536935 | 0.84 | NPSR1 (0.55) | RAB9ASSTR5HRH1CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |