Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460066 | 0.84 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1HPGDUSP2 | |
| SCHEMBL3660770 | 0.83 | SRD5A2 (0.51) | KDM4EHSD17B10ALDH1A1HPGDSRD5A2 | |
| SCHEMBL5992479 | 0.83 | CNR2 (0.55) | KDM4EHSD17B10HPGDSRD5A2USP2 | |
| SCHEMBL1513062 | 0.83 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1HPGDSRD5A2 | |
| SCHEMBL30070755 | 0.83 | CNR2 (0.55) | KDM4EHSD17B10HPGDSRD5A2USP2 | |
| SCHEMBL5723651 | 0.83 | TDP1 (0.82) | KDM4ETDP1AKR1C3HSD17B10ALDH1A1 | |
| SCHEMBL29941444 | 0.83 | SRD5A2 (0.51) | KDM4EHSD17B10ALDH1A1HPGDSRD5A2 | |
| SCHEMBL3486347 | 0.83 | MAPT (0.61) | KDM4EHSD17B10ALDH1A1HPGDSRD5A2 | |
| SCHEMBL38533242 | 0.83 | AKR1C3 (0.66) | KDM4EAKR1C3HSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL11751786 | 0.83 | AKR1C3 (0.66) | KDM4EAKR1C3HSD17B10ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575425-A1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016207-A1 | USE OF OXAZOLO-[2,3-a]ISOINDOLE AND IMIDAZO[2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO[2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |