Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535611 | 0.81 | PTGS2 (0.56) | SLC22A12PTGS2PARP14NR3C1TNIK | |
| SCHEMBL9535031 | 0.72 | PTGS2 (0.55) | SLC22A12PTGS2PARP14PTGS1 | |
| SCHEMBL897113 | 0.70 | PARP14 (0.47) | SLC22A12PARP14NR3C1TNIKPGR | |
| SCHEMBL10622738 | 0.69 | PTGS2 (0.41) | SLC22A12PTGS2PARP14NR3C1SMN1; SMN2 | |
| SCHEMBL4593012 | 0.69 | TNIK (0.48) | SLC22A12PARP14NR3C1TNIKPGR | |
| SCHEMBL6389949 | 0.68 | SLC22A12 (0.47) | SLC22A12PARP14NR3C1TNIKPGR | |
| SCHEMBL4641810 | 0.68 | SLC22A12 (0.54) | SLC22A12PARP14NR3C1TNIKPGR | |
| SCHEMBL2005491 | 0.68 | SLC22A12 (0.47) | SLC22A12PARP14NR3C1PGR | |
| SCHEMBL9340013 | 0.66 | PARP14 (0.48) | SLC22A12PARP14NR3C1TNIKPGR | |
| SCHEMBL12060800 | 0.66 | SLC22A12 (0.45) | SLC22A12PARP14NR3C1TNIKPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |