Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.71 |
| ▸ | PPARA | Q07869 | 16/20 | 0.71 |
| ▸ | PPARD | Q03181 | 9/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142951 | 0.94 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL3279259 | 0.89 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL4389208 | 0.88 | PPARG (0.79) | PPARGPPARAPPARD | |
| SCHEMBL16144192 | 0.88 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL14382549 | 0.88 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL4029375 | 0.88 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL3279660 | 0.88 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL7736876 | 0.88 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL3283978 | 0.87 | PPARG (0.77) | PPARGPPARAPPARD | |
| SCHEMBL5112238 | 0.86 | PPARG (0.76) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939188-A1 | Oxa-and thiazole derivatives useful as antidiabetic and antiobesity agents | Bristol-Myers Squibb Company (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-0544696-A1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES. | PFIZER HOSPITAL PROD (US) | 1993-06-09 | — | — | EP | disclosed |