Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537324 | 0.73 | HDAC1 (0.38) | HPRT1HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL10510295 | 0.69 | HDAC1 (0.44) | HDAC1HDAC2HDAC6PNPHDAC4 | |
| SCHEMBL8990463 | 0.68 | CYP2C19 (0.43) | HPRT1PNP | |
| SCHEMBL1663801 | 0.68 | HDAC1 (0.43) | HPRT1HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1663924 | 0.68 | HDAC1 (0.43) | HPRT1HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1663919 | 0.68 | HDAC1 (0.43) | HPRT1HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL8816230 | 0.67 | HDAC1 (0.35) | HPRT1HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1444329 | 0.65 | NT5E (0.36) | HDAC1HDAC2HDAC6HDAC4NT5E | |
| SCHEMBL5962141 | 0.65 | HSP90AB1 (0.38) | HDAC1HDAC2HDAC6HDAC4HSP90AA1 | |
| SCHEMBL6940477 | 0.65 | HSP90AB1 (0.38) | HDAC1HDAC2HDAC6HDAC4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |