Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311436 | 0.79 | MIF (0.39) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9311479 | 0.79 | ALDH1A1 (0.43) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5164145 | 0.77 | ALDH1A1 (0.48) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9311119 | 0.76 | CHRM1 (0.36) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1020285 | 0.74 | TP53 (0.42) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9741692 | 0.72 | MIF (0.48) | MIFALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL29188584 | 0.72 | PTGDR2 (0.42) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1021879 | 0.72 | HTR2B (0.34) | MIFCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5050876 | 0.71 | CYP1A2 (0.52) | CYP1A2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11996517 | 0.71 | ALDH1A1 (0.46) | MIFCYP1A2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |