Urethane

Urethane

SCHEMBL9537722

CCOC(N)=O.N=C=O.NC(=O)NC(N)=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.60
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
CAD P27708 1/20 0.36
ALDH1A1 P00352 6/20 0.36
MAPT P10636 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 3/20 0.34
HSD17B10 Q99714 2/20 0.34
CRBN Q96SW2 1/20 0.34
SOAT1 P35610 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL16384673 0.92 ALOX15 (0.56) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL370763 0.89
Urethane SCHEMBL7906206 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL27759655 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL28558256 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL11444589 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL1930430 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL11803069 0.89 ALOX15 (0.75) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL7100083 0.87 ALOX15 (0.71) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL10779791 0.87 ALOX15 (0.71) ALOX15GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157611-B1 Fluorochemical biuret compositions and fibrous substrates treated therewith MINNESOTA MINING & MFG (US) 1993-11-10 EP disclosed
US-4748267-A Fluorochemical biuret compounds and fibrous substrates treated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-05-31 US disclosed
US-4668406-A OIL REPELLENTS, WATERPROOFING, ANTISOILANTS, FLUOROALIPHATIC POLYOXYALKYLENE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-26 US disclosed
EP-0157611-A1 Fluorochemical biuret compositions and fibrous substrates treated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-09 EP disclosed