Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459773 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRD1L3MBTL1BCHE | |
| SCHEMBL2459774 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRD1L3MBTL1BCHE | |
| Salicylic Acid SCHEMBL9538265 | 0.91 | BCHE (0.48) | OPRM1OPRK1OPRD1L3MBTL1BCHE | |
| SCHEMBL9540882 | 0.86 | BCHE (0.55) | BCHEACHE | |
| SCHEMBL2459728 | 0.86 | BCHE (0.55) | BCHEACHE | |
| SCHEMBL2459729 | 0.86 | BCHE (0.55) | BCHEACHE | |
| Bromide SCHEMBL9539186 | 0.85 | BCHE (0.54) | BCHEACHE | |
| SCHEMBL9537701 | 0.84 | OPRM1 (0.47) | OPRM1OPRK1OPRD1 | |
| SCHEMBL9539147 | 0.83 | OPRM1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL2455820 | 0.83 | BCHE (0.51) | OPRM1OPRK1OPRD1L3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |