Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460463 | 1.00 | BCHE (0.38) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL2460461 | 1.00 | BCHE (0.38) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL2462293 | 0.89 | BCHE (0.48) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL2462297 | 0.89 | BCHE (0.48) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL8863169 | 0.84 | OPRM1 (0.51) | KDM4ETP53ALOX15MAPTSIGMAR1 | |
| SCHEMBL2455595 | 0.84 | OPRM1 (0.51) | KDM4ETP53ALOX15MAPTSIGMAR1 | |
| SCHEMBL2455610 | 0.82 | KDM4E (0.39) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL9538484 | 0.82 | KDM4E (0.39) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL2455609 | 0.82 | KDM4E (0.39) | BCHEACHEKDM4ETP53ALOX15 | |
| SCHEMBL2456414 | 0.82 | KDM4E (0.56) | BCHEACHEKDM4ETP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |