Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539379 | 1.00 | PTPN1 (0.50) | PTPN1CA12CA9CA1CA2 | |
| SCHEMBL29466657 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL20777531 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL13990666 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL15065526 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL29355036 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL16069592 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL16069671 | 0.80 | APP (0.55) | CA12CA9CA1CA2TNF | |
| SCHEMBL8634263 | 0.77 | CA12 (0.69) | PTPN1CA12CA9CA1CA2 | |
| SCHEMBL3022467 | 0.77 | CA12 (0.69) | PTPN1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242805-A | Useful in directingcells producing enzymes that hydrolyze the glycoside | MOLECULAR PROBES, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993004074-A1 | LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |