Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860401 | 0.87 | — | — | |
| SCHEMBL3371973 | 0.76 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27888136 | 0.76 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL23544787 | 0.76 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9975188 | 0.76 | SMN1; SMN2 (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16047312 | 0.74 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9936567 | 0.73 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL23919095 | 0.73 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1665375 | 0.73 | SMN1; SMN2 (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL3373683 | 0.71 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5032857-A | — | — | None | — | — | JP | disclosed |
| JP-H0532857-A | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO | 1993-02-09 | — | — | JP | disclosed |