Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007519 | 0.78 | ALOX5 (0.48) | ALOX5DHODHGAANPSR1MEN1 | |
| SCHEMBL9541332 | 0.77 | ALOX5 (0.44) | ALOX5DHODHGAANPSR1MEN1 | |
| Phenoxazine SCHEMBL6310178 | 0.71 | ALOX5 (1.00) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL7862 | 0.71 | ALOX5 (1.00) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL29355714 | 0.71 | ALOX5 (1.00) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL28844098 | 0.71 | ALOX5 (1.00) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL25275195 | 0.69 | ALOX5 (0.94) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL5808288 | 0.69 | ALOX5 (0.94) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL20840431 | 0.69 | ALOX5 (0.94) | ALOX5DHODHGAANPSR1PARP1 | |
| Phenoxazine SCHEMBL29212121 | 0.69 | ALOX5 (0.94) | ALOX5DHODHGAANPSR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000883-A1 | USE OF 1,9-DIHYDRO-PYRAZOLO[4,3-B][1,4]-BENZOXAZINES AS COUPLERS FOR OXIDATION DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-01-21 | — | — | WO | disclosed |
| US-4552874-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |