Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538354 | 1.00 | LMNA (0.44) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL37683 | 0.96 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL896585 | 0.92 | LMNA (0.37) | LMNATHRB | |
| SCHEMBL760448 | 0.92 | LMNA (0.33) | LMNA | |
| SCHEMBL758679 | 0.92 | LMNA (0.33) | LMNA | |
| SCHEMBL8060577 | 0.92 | LMNA (0.33) | LMNA | |
| SCHEMBL10534900 | 0.89 | LMNA (0.35) | LMNA | |
| SCHEMBL4977272 | 0.88 | LMNA (0.32) | LMNA | |
| SCHEMBL9538166 | 0.88 | — | — | |
| SCHEMBL10381191 | 0.85 | LMNA (0.37) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005200-A1 | AZEOTROPE-LIKE COMPOSITIONS OF 1,1-DICHLORO-1-FLUOROETHANE AND PERFLUOROCARBONS AND OPTIONALLY NITROMETHANE | ALLIED-SIGNAL INC. (US) | 1993-03-18 | — | — | WO | disclosed |