Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662955 | 0.83 | CCKAR (0.57) | CCKBR | |
| SCHEMBL6892993 | 0.83 | CCKAR (0.57) | CCKBR | |
| SCHEMBL7817204 | 0.81 | CCKBR (0.56) | CCKBRNMBRMAPTALDH1A1MEN1 | |
| SCHEMBL8829876 | 0.80 | CCKBR (0.68) | CCKBRNMBRMAPTALDH1A1MEN1 | |
| SCHEMBL7820011 | 0.80 | CCKBR (0.59) | CCKBRNMBRMAPTALDH1A1MEN1 | |
| SCHEMBL7820013 | 0.80 | CCKBR (0.59) | CCKBRNMBRMAPTALDH1A1MEN1 | |
| SCHEMBL6892425 | 0.77 | CCKBR (0.78) | CCKBRNMBR | |
| SCHEMBL10629963 | 0.77 | CCKBR (0.59) | CCKBRNMBRSIRT2 | |
| SCHEMBL8829834 | 0.76 | CCKBR (0.61) | CCKBRNMBR | |
| SCHEMBL8829838 | 0.76 | CCKBR (0.61) | CCKBRNMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |