Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539879 | 0.99 | KMT2A (0.55) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9537740 | 0.94 | KMT2A (0.58) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9537382 | 0.93 | KMT2A (0.59) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9536803 | 0.93 | KMT2A (0.55) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL27789137 | 0.92 | KMT2A (0.52) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9539001 | 0.92 | KMT2A (0.55) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL11017455 | 0.90 | LMNA (0.62) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9538141 | 0.90 | LMNA (0.66) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL11017753 | 0.90 | KMT2A (0.52) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9535903 | 0.85 | KMT2A (0.61) | KMT2AEPHA2FLT4GSK3BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153580-B2 | NAPHTHYRIDINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0153580-A1 | Naphthyridine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-04 | — | — | EP | disclosed |