Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536230 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1MAPTUSP7USP10 | |
| SCHEMBL9534367 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1MAPTKMT2AUSP7 | |
| SCHEMBL9868559 | 0.80 | PTGS2 (0.48) | PTGS2PTGS1MAPTCMA1SMN1; SMN2 | |
| SCHEMBL9535471 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1MAPTUSP7USP10 | |
| SCHEMBL9538909 | 0.77 | PTGS2 (0.53) | PTGS2PTGS1MAPTKMT2AUSP7 | |
| SCHEMBL9537417 | 0.77 | PTGS2 (0.55) | PTGS2PTGS1SMN1; SMN2GAAACLY | |
| SCHEMBL9536305 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1KMT2APOLBLMNA | |
| SCHEMBL9536928 | 0.76 | PTGS2 (0.54) | PTGS2PTGS1POLBLMNA | |
| SCHEMBL9537336 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1POLBLMNAGAA | |
| SCHEMBL9537146 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |