Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9534482 | 0.88 | SSTR5 (0.49) | SSTR5TP53ENPP2DRD4DRD2 | |
| SCHEMBL9537229 | 0.88 | SSTR5 (0.56) | SSTR5ENPP2DRD4DRD2DRD3 | |
| SCHEMBL9536516 | 0.86 | SSTR5 (0.52) | SSTR5TP53DRD4DRD2DRD3 | |
| SCHEMBL9535999 | 0.85 | SSTR5 (0.56) | SSTR5DRD4DRD2DRD3MAPT | |
| Oxalic Acid SCHEMBL10383157 | 0.85 | SSTR5 (0.47) | SSTR5TP53ENPP2DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL9538066 | 0.85 | SSTR5 (0.52) | SSTR5TP53DRD4DRD2DRD3 | |
| Oxalic Acid SCHEMBL10383159 | 0.84 | ALDH1A1 (0.49) | SSTR5TP53ENPP2DRD4DRD2 | |
| Oxalic Acid SCHEMBL10383158 | 0.84 | ALDH1A1 (0.49) | SSTR5TP53ENPP2DRD4DRD2 | |
| SCHEMBL10384106 | 0.83 | SSTR5 (0.47) | SSTR5TP53ENPP2DRD4DRD2 | |
| SCHEMBL11471515 | 0.81 | TP53 (0.61) | SSTR5TP53ENPP2MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |