Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589635 | 0.80 | TAAR1 (0.46) | — | |
| SCHEMBL11401428 | 0.80 | HTT (0.49) | SCN9A | |
| SCHEMBL8046330 | 0.78 | SCN9A (0.46) | SCN9AHTR2CDRD2DRD4DRD3 | |
| SCHEMBL11390243 | 0.77 | HSD17B2 (0.48) | HTR2C | |
| SCHEMBL9485742 | 0.74 | KDM1A (0.40) | SCN9ASLC6A4SLC6A3CHRM2 | |
| SCHEMBL19244969 | 0.74 | SCN9A (0.47) | SCN9AGPR84DAO | |
| SCHEMBL19043747 | 0.74 | SLC6A4 (0.46) | SCN9AGPR84SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL11393064 | 0.74 | HRH1 (0.42) | — | |
| SCHEMBL11395955 | 0.74 | TAAR1 (0.41) | — | |
| SCHEMBL11407097 | 0.74 | MMP12 (0.55) | SCN9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| US-4275201-A | Aryl substituted diketones | STERLING DRUG INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4189500-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4171378-A | INSECTICIDES, VIRICIDES | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4166074-A | DIALKYLAMINOPHENYLETHYL (OR VINYL) CYCLOPROPYL CARBINOLS | STERLING DRUG INC. (US) | 1979-08-28 | — | — | US | disclosed |
| US-4125541-A | Aryl substituted ketones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125714-A | Aryl substituted cycloalkanones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |