Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589197 | 0.88 | ADRB2 (0.76) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9533664 | 0.88 | ADRB2 (0.76) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9589192 | 0.88 | ADRB2 (0.76) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9540272 | 0.86 | KMT2A (0.77) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9537333 | 0.84 | KMT2A (0.77) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9536912 | 0.84 | KMT2A (0.74) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| Oxalic Acid SCHEMBL9589148 | 0.84 | ADRB2 (0.73) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9536941 | 0.83 | KMT2A (0.70) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL9536937 | 0.83 | KMT2A (0.72) | KMT2AADRB2ADRB1CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL9588039 | 0.83 | KMT2A (0.76) | KMT2AADRB2ADRB1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |