Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539767 | 0.81 | AKR1B1 (0.48) | AKR1B1PGRGAAMEN1MAPT | |
| SCHEMBL9540059 | 0.80 | PGR (0.40) | AKR1B1PGRMAPT | |
| SCHEMBL9539042 | 0.75 | — | — | |
| SCHEMBL9539048 | 0.73 | PGR (0.40) | AKR1B1PGRGAAKDM4EMEN1 | |
| SCHEMBL9542678 | 0.72 | AKR1B1 (0.38) | AKR1B1PGRGAAMEN1MAPT | |
| SCHEMBL9539751 | 0.71 | AKR1B1 (0.38) | AKR1B1PGRGAAMEN1MAPT | |
| SCHEMBL9539046 | 0.71 | PGR (0.38) | PGRMAPT | |
| SCHEMBL18095002 | 0.68 | PGR (0.53) | PGRGAAMAPTMGAMHTR1A | |
| SCHEMBL30548477 | 0.68 | PGR (0.53) | PGRGAAMAPTMGAMHTR1A | |
| SCHEMBL18095005 | 0.68 | PGR (0.53) | PGRGAAMAPTMGAMHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530994-A1 | Quinazoline derivatives as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1993004047-A1 | QUINAZOLINE DERIVATIVES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1993-03-04 | — | — | WO | claimed |