Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 1.00 |
| ▸ | BCHE | P06276 | 3/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | USP2 | O75604 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387188 | 0.93 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL29416837 | 0.93 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30600296 | 0.92 | MEN1 (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969327 | 0.78 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968424 | 0.78 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968422 | 0.78 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969212 | 0.78 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL6921297 | 0.78 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969488 | 0.78 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968453 | 0.78 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |